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“Biobehavioral Utility of Mindfulness-Based Art Therapy: Neurobiological Underpinnings and Mental Health Impacts.” Experimental Biology and Medicine 245, no. 2 (January 2020): 122–30.
“Research Review: The Effects of Mindfulness‐based Interventions on Cognition and Mental Health in Children and Adolescents – a Meta‐analysis of Randomized Controlled Trials.” Journal of Child Psychology and Psychiatry, and Allied Disciplines 60, no. 3 (March 2019): 244–58.
“Mindfulness-Based Treatment of Addiction: Current State of the Field and Envisioning the next Wave of Research.” Addiction Science & Clinical Practice 13 (2018): 14.
“Mindfulness-Based Interventions for Psychiatric Disorders: A Systematic Review and Meta-Analysis.” Clinical Psychology Review 59 (February 2018): 52–60.
.“The Relationship between Mindfulness and Emotional Intelligence as a Protective Factor for Healthcare Professionals: Systematic Review.” International Journal of Environmental Research and Public Health 18, no. 10 (May 20, 2021): 5491.
Kral, Tammi R. A., Brianna S. Schuyler, Jeanette A. Mumford, Melissa A. Rosenkranz, Antoine Lutz, and Richard J. Davidson. “Impact of Short- and Long-Term Mindfulness Meditation Training on Amygdala Reactivity to Emotional Stimuli.” NeuroImage 181 (November 1, 2018): 301–13.
Mehta, Ria, Kirti Sharma, Louis Potters, A. Gabriella Wernicke, and Bhupesh Parashar. “Evidence for the Role of Mindfulness in Cancer: Benefits and Techniques.” Cureus 11, no. 5 (n.d.): e4629.
Parra, Diana C., Julie Loebach Wetherell, Alexandria Van Zandt, Ross C. Brownson, Janardan Abhishek, and Eric J. Lenze. “A Qualitative Study of Older Adults’ Perspectives on Initiating Exercise and Mindfulness Practice.” BMC Geriatrics 19, no. 1 (December 23, 2019): 354.
Sathyanarayanan, Gopinath, Ashvini Vengadavaradan, and Balaji Bharadwaj. “Role of Yoga and Mindfulness in Severe Mental Illnesses: A Narrative Review.” International Journal of Yoga 12, no. 1 (April 2019): 3–28.
Tement, Sara, Zalika Klemenc Ketiš, Špela Miroševič, and Polona Selič-Zupančič. “The Impact of Psychological Interventions with Elements of Mindfulness (PIM) on Empathy, Well-Being, and Reduction of Burnout in Physicians: A Systematic Review.” International Journal of Environmental Research and Public Health 18, no. 21 (October 25, 2021): 11181.
Watson, Tayler, Owen Walker, Robin Cann, and Ashwin K. Varghese. “The Benefits of Mindfulness in Mental Healthcare Professionals.” F1000Research 10 (2021): 1085.
“Effectiveness of Mindfulness Meditation vs Headache Education for Adults With Migraine: A Randomized Clinical Trial.” JAMA Internal Medicine 181, no. 3 (March 1, 2021): 317–28.
Zeidan, Fadel, and David Vago. “Mindfulness Meditation–Based Pain Relief: A Mechanistic Account.” Annals of the New York Academy of Sciences 1373, no. 1 (June 2016): 114–27.
Zhang, Dexing, Eric K. P. Lee, Eva C. W. Mak, C. Y. Ho, and Samuel Y. S. Wong. “Mindfulness-Based Interventions: An Overall Review.” British Medical Bulletin 138, no. 1 (June 10, 2021): 41–57.

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Anxiety, Depression, and Insomnia Treatment Benefits Products

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Anxiety, Depression, and Insomnia Treatment Benefits Products

Researchers have found that CBD is effective for a variety of ailments, including anxiety, depression, and insomnia. In a recent study, 430 individuals participated in a survey regarding the benefits of CBD. Of these, 15 did not respond to any questions and 28 did not report using CBD. However, these non-users shared similar sociodemographic characteristics with those who did use CBD. Among those who answered the survey, 387 individuals said that they had used CBD for a variety of medical conditions, including anxiety, depression, and insomnia. These surveys also found that most CBD users were females in the UK. Another study surveyed 400 CBD patients from New Zealand.

Despite its widespread use, not enough clinical trials have been conducted. However, a review of these studies indicates that there is a growing body of evidence supporting CBD’s potential benefits for a variety of neurological and mental health conditions. For example, a recent study in Neurotherapeutics concluded that topical CBD may have a positive effect on multiple anxiety disorders. Further, in September 2015, the Journal of the American Society for Experimental NeuroTherapeutics published a review of this study. This study shows that there is a great deal of preclinical evidence for CBD’s effectiveness in anxiety disorders.

CBD also inhibits the formation of amyloid plaques in vitro. A study by Libro et al. found that CBD inhibited the expression of the enzyme GDK3b, a key factor in AD pathogenesis. Moreover, CBD stimulates the production of neurons in the brain and has neuroprotective effects.

In animal models of schizophrenia, CBD has shown positive effects in improving psychotic symptoms. In one study, it lowered stereotypy in rats similar to haldol. In mice, CBD exhibited similar effects to clozapine and haloperidol. In addition, the drug did not cause catatonia or any other side effects of conventional medications.

CBD has a low toxicity profile and no abuse or dependency potential. Its safety profile is excellent, and the European Union has classified CBD as a novel food. However, regulations vary from country to country. For instance, in the UK, the Food Standards Agency recommends a daily dose of 70 mg of CBD for adults. However, researchers have used as much as 1200 mg per day without any serious adverse effects.

In clinical trials, CBD has shown potential anti-tumor effects. In one study, it increased the expression of ICAM-1, an intercellular adhesion molecule. This protein is negatively correlated with cancer metastasis. Furthermore, CBD increased ICAM-1 expression in lung cancer cell lines, reducing their invasiveness.

However, further research is needed to determine whether CBD is addictive. It should be tested on larger patient cohorts and a longer follow-up period. As a sedative, CBD may cause problems when used in high doses. It may also lead to a dependency, which is dangerous for people who take it for a long time.